Protein sequence identification, assignment and validation with FindMySequence -Grzegorz Chonjnowski
Amino acid sequence is an indispensable prerequisite of protein model building in MX and EM. Unless very high resolution data are available, the sequence is required to place half of the model atoms and identify and complete poorly resolved model regions. At the same time, however, it is astonishingly easy to introduce sequence assignment errors that may bias model interpretation.
In my talk I will present findMySequence, a tool for identifying protein model sequence in cases where it is not known prior to the structure determination process. I will also introduce a related method, checkMySequence, for fast and conceptually simple identification of sequence assignment errors in protein models.