Review M-Audio Oxygen 49 (3rd gen) and fixing midi error

Опубликовано: 12 Апрель 2026
на канале: tricks-and-tips
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A short review of the M-Audio Oxygen 49 midi controller (3rd gen).

I really like this controller, because it makes my music - editing in Reason a lot more easy, since I don't have to operate all the controls with my mouse, and I can stay behind the keys.

Summing up:
Pro:
Small enough to store
Big enough to fit 49 keys
Enough controllers to conveniently edit Propellerhead Reason instruments
Nicely priced.

Con:
Keys have a little bit of plastic feal.
Issue while connecting for the first time (see solution below)

MIDI PROBLEM:
While trying to connect the M-Audio49 to Reason, I got the error:
"MIDI PROBLEM:
The midi port may be in use by another application"

So how did I fix that?
I had to dig into the Windows registry.
So no warranties here, make a backup from the registry if you're not comfortable.

To edit the registry, Hold the Windows Key and press R (run)
Type 'Regedit' and click 'OK'.
Making the backup can be done by clickin 'File \ Export' and save the file somwhere.

Now find
HKEY_LOCAL_MACHINE\SYSTEM\ControlSet001\Control\Class\

Find the key {4D36E96C-E325-11CE-BFC1-08002BE10318}

Here we have to add a missing key, so right click in the left part.
Select 'New \ Multi string value'
Give it the name 'UpperFilters'

Double click this filter and add the value data:
ksthunk

Click 'OK'.

Close the registry editor.

restart you're PC.

Start Reason or some other program.