Sainte-Mère-Église lies in a flat area of the Cotentin peninsula known locally as le Plain.
The Plain is bounded on the west by the Merderet River and by the English channel to the east, and by the communes of Valognes and Carentan to the north and south, respectively. Besides Sainte-Mère-Église, the Plain's other major town is Montebourg, and its coast includes Utah Beach.
A well-known incident involved paratrooper John Steele of the 505th Parachute Infantry Regiment (PIR), whose parachute caught on the spire of the town church, and could only observe the fighting going on below. He hung there limply for two hours, pretending to be dead, before the Germans took him prisoner. Steele later escaped from the Germans and rejoined his division when US troops of the 3rd Battalion, 505 Parachute Infantry Regiment attacked the village, capturing thirty Germans and killing another eleven.