What Is UCTD? Understanding Undifferentiated Connective Tissue Disease | Dr. Stermer Explains
In this video, Dr. Clifford Stermer from One Rheumatology explains Undifferentiated Connective Tissue Disease (UCTD)—a real and surprisingly common autoimmune condition affecting up to 25% of patients seen in rheumatology clinics. UCTD describes people who have autoimmune symptoms but don’t meet full criteria for lupus, rheumatoid arthritis, or another defined connective tissue disease.
Dr. Stermer discusses how UCTD may develop in individuals with a genetic predisposition to autoimmunity, potentially triggered by environmental factors such as infections. He walks through the common symptoms, including joint pain, joint swelling, Raynaud’s phenomenon, dry eyes, dry mouth, photosensitive rashes, mouth or nose ulcers, hair loss, and in rare cases, inflammatory fluid around the heart or lungs (pericarditis or pleuritis).
This video is for informational purposes only and is not medical advice. If you’re experiencing these symptoms or wonder whether your autoimmune condition fits a specific category, speak with your rheumatologist.
Have questions about UCTD or other autoimmune conditions? Leave them in the comments, and we’ll continue creating educational videos to help guide you.