Histone Acetylation | Epigenetics
Histone acetylation is a critical post-translational modification of histone proteins that plays a key role in regulating gene expression. It occurs when acetyl groups (−𝐶𝑂𝐶𝐻3) are added to the lysine residues of histone proteins, particularly on the N-terminal tails, by specific enzymes called histone acetyltransferases (HATs). This process alters the chromatin structure and affects the accessibility of DNA to transcriptional machinery.
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