In this episode, I briefly cover the Meningioma section from Kurt’s Notes. Meningiomas are dural-based CNS tumors, the most common brain tumors in adults.
Knowing the various features and criteria that can make meningiomas a higher grade is important. I didn’t mention it in the video, but there are molecular findings that can make a meningioma a WHO Grade III entity, such as TERT promoter mutations or homozygous deletions of CDKN2A or CDKN2B. Consider sending the tumor out for NGS (Next-generation sequencing) if you have enough tissue and various features of the lesion concern you. This topic is discussed here at https://www.ncbi.nlm.nih.gov/pmc/arti....
Another excellent resource for Meningiomas is this lecture on PathCast by Dr. Rodriguez ( • Meningiomas - Dr. Rodriguez (Hopkins) #NEU... ).
Check out Kurt's Notes CNS Tumors section for great material on Neuropathology (https://schaberg.faculty.ucdavis.edu/).
I hope to apply for a Neuropathology fellowship slot and have a long way to go in my studies. But we all get better one day and one study session at a time. Have a good week, everybody.
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