Inferno S-Rank with Unlocks | Resident Evil 3 - 2020 Remake
Perhaps one of the most hardest difficulties offered in the game, made even harder by the RNG of stage-3 Nemesis. This is the complete run with deaths/failed attempts cut out except for those during the final boss fight. My run in this video heavily relies on unlockable coins, infinite ammo weapons, the dodge assist journal, etc. No way in hell will I ever do this run without the coins at the very least... I've only ever completed Inferno difficulty twice as of this video. (First was on console, second on PC.)
Timestamps/Chapters (sorted by chapter objectives)
00:00 Escape the apartment complex
DOWNTOWN RACCOON CITY (Jill)
01:59 Get out of town
03:39 Go to the rooftop parking lot
04:51 Go with Carlos
05:49 Get above ground
11:04 Reactivate power at the substation
15:49 Bring the trains online in the subway office
SUBWAY
18:58 Return to the subway station
21:37 Lure the creature away from the subway station
SEWERS
22:35 Find a way above ground
DEMOLITION SITE
26:13 Escape the creature (Flamethrower)
28:22 Defeat the creature - Nemesis Stage-1
DOWNTOWN RACCOON CITY
28:55 Return to the subway station
31:23 Escape the creature (Rocket Launcher)
33:38 Go to the subway platform
RACCOON CITY POLICE DEPARTMENT (Carlos)
34:45 Find Dr. Bard
CLOCK TOWER (Jill)
41:36 Find a way above ground
42:38 Escape the creature
43:08 Defeat the creature - Nemesis Stage-2
HOSPITAL (Carlos)
43:48 Search for a vaccine
49:14 Give the vaccine to Jill
49:58 Defend Jill
54:27 Place the detonator
54:43 Hold out until the explosion
HOSPITAL (Jill)
55:30 Leave the sickroom
55:33 Head to the underground facility
UNDERGROUND FACILITY
57:30 Restore power to the elevator
1:00:56 Pursue Nicholai
1:01:10 Get the vaccine (Go with Tyrell)
1:01:54 Get the vaccine
1:07:22 Escape the facility
1:08:07 Defeat the creature - Nemesis Stage-2.5
1:09:25 Defeat the creature - Nemesis Stage-3 (Final Mutation, Failed Attempts)
1:13:12 Defeat the creature - Nemesis Stage-3 (Final Mutation, Successful Attempt)
1:16:18 Take back the vaccine
1:17:25 Results
Best strategy for the final Nemesis: stay cool, calm and collected, and learn its movements to prepare a dodge. (Not always successful, he can stun lock kill. If that happens, try to heal.)