A guide to unlocking all 16 artifacts in the Risk of Rain 2 Artifact update. This will be the quickest way to legitimately unlock artifacts.
To unlock artifacts in risk of rain 2 you need to first get to sky meadow, a brand new stage 5 area, and then input a code in a specific sequence at the compound generator. After activating the code at the laptop you can go through a teleporter and fight the Artifact Reliquary by collecting and using artifact keys on it repeatedly. Defeating the Artifact Reliquary will cause it to drop the artifact whose code you used to get to Bulwark's Ambry. You can then use the teleport out and continue on your loop.
There are 16 total artifacts and each has a unique code that can be found by going to specific locations throughout your runs. If you'd rather not go scavenger hunting the list of codes will be on your screen. I'll have a link to the image so you can save it on your computer. I am completing the Artifact of Command in this video so if you want to unlock that artifact I recommend following along with the video.
The boss fight does not change regardless of whatever artifact you use. That being said, the artifact that you choose will be active during the boss fight so be aware of that if you are trying to unlock a difficult artifact modifier.
https://riskofrain2.gamepedia.com/Art...