Primary Amenorrhea : Causes , Diagnosis and Treatment

Опубликовано: 19 Июль 2026
на канале: AAUN Obs and Gynae

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Primary amenorrhea is defined as the absence of menses at age 15 years in the presence or absence of normal growth and secondary sexual characteristics. The identification of primary amenorrhea should always prompt a thorough evaluation to identify a cause . There are various causes behind Primary amenorrhea such as Chromosomal or Genetic Abnormalities, Turner syndrome, Androgen Insensitivity Syndrome and problems with the hypothalamus or pituitary gland in the brain can cause an imbalance of hormones that can prevent periods from starting.
This video is about diagnostic tests used in the evaluation of Primary amenorrhea. Different tests used in Primary amenorrhea diagnosis include Blood tests like FSH / LH, Serum Prolactin, 17 alpha hydroxyprogesterone level to diagnose congenital adrenal hyperplasia, 5 alpha reductase level, serum Testosterone level, DHEA (De hydro epi aldosterone) level. Apart from the blood tests we do other tests like Pelvic Ultrasound to diagnose adrenal and ovarian tumors, Karyotyping, Advance Imaging Modalities like CT scan and Gonadal Biopsy etc. This topic has also been explained by Lecturio Medical and for this video reference has been taken from Arshad Chohan book . Primary amenorrhea is infact defined as absence of menstrual cycle in the presence or absence of growth or secondary sexual characteristics.
The different management options in primary amenorrhea include growth hormones , estrogen therapy , surgical techniques like Laparoscopic Ovarian drilling etc if PCOD is diagnosed . The management of primary amenorrhea depends on the choices of patients about future intentions of fertility .
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