Item Asylum Perfect Run Boss Guide (Outdated)
(Reuploaded twice due to video mismatch & changes to the music and text)
This video will go over every boss in Item Asylum with a perfect run badge; their moves, tips and strategies, sound effects and the best items for each boss.
#itemasylum
This video is outdated after the Spring update (18/05/2026), a new boss was added and most of the bosses have new changes to their AI and other differences such as new attacks
I hope I was able to help in any shape or form, I'd like to make more videos like this
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TOP RECOMMENDED ITEMS:
Good Boss items in general:
Damage-required items are always good in Boss (Lilynette, Bugle, Master Spark etc), Speed (Cassiebucks, Skeleton Juice etc), Jump (Space Sandwich, Super Scuffle etc), Healing (Chirumiru, Chicken Sandwich, Darkheart etc), Parry (Legion Kata, Hero Blade, Brutalizer etc), Inv. Frames (Ashura Senku, Cresendo's dash etc), '2nd lives' (Pizza Knife, Joy etc)
10 Hour Burst Man
High Damage/DPS Melee (Your Eternal Reward, Fire Axe, Crowbar, Banhammer etc)
High Damage/DPS Ranged (Airpod Shotty, Asteroid, Chicago, Crossbow, Dinner Blaster etc)
Speed, Healing, Parry, I-frames & 2nd lives extremely help
Beta
Ranged Melee (Hat of Discipline etc)
High DPS Ranged/Hitscans (Chicago, Dinner Blaster, Hyperlaser etc)
Speed, Healing, Jump, Parry, I-Frame and 2nd lives are extremely helpful
Clayman
Rukiryaxe (solo), Shadow Axe (with teammates), Fire Axe if experienced, Axe for mobility
Contamination
Mad Noob Shotgun, Suppressed Mac-10, Micro SMG, Hyperlaser (pierces), Pixel Rifle, Trench Shotgun & HS-010 (knockback ability), guns cannot upgrade, you need the actual upgrade itself, forgot to mention in video
Klevprime
High DPS Melees, High DPS ranged (slungusprism)
Jump, Speed, Healing, Parry, I-frames and 2nd lives help a lot
Man of Nature
Ranged/Crowd Control Melees (Hat of Discipline, Voice Acted Sword, Freezing Point, Broadsword, Buster Sword, Comically Large utensils etc)
All upgradable Melees are very helpful (Small Sword, Table, Lamp, Photon Blades etc)
Speed, Jump, Healing, Parry, I-frames and 2nd lives help a lot
Matter
Curse (Shadow Axe, Secare, Judge, Solemn Lament, Icecream Treat etc)
High DPS/Ranged Melees + Ranged (Freezing Point, Darkheart, Asteroid, Dinner Blaster etc) in case of Poison form
Speed, Jump, Healing, Parry, I-frames and 2nd lives help significantly
Sage
DPS Melees (if doing pillar/somersault bait strategy)
DPS Ranged (Chicago, Dinner Blaster, Asteroid etc)
Speed, Jump, Healing, Parry, I-Frames and 2nd lives help significantly
Skeleton
DPS/Ranged Melee for Phase 3 (Hat of Discipline, Darkheart etc)
DPS Ranged (Chicago, Lightning Harp Crossbow, HS-010, Hound, Asteroid etc)
Speed, Jump, Healing, Parry, I-frames and 2nd lives are extremely helpful
Trash Gang
Hitscan Ranged (Makarov, M1911, Chicago, Etymology, Ssg-08 etc)
Jump, Healing and 2nd lives are very helpful (all attacks by enemies bypass parry/i-frames, forgot to mention in video)
Uncertified
Upgradable Melees (Large Sword, Photon Blades, Lamp, Chair etc)
Upgradable Ranged (Pixel Gun, Ssg-08, 9mm, M1911, Suppressed Pistol etc)
Speed, Jump, Healing, Parry, I-frame and 2nd lives exponentially help, especially for Minos/Dracombat
Weegee
Knockback/Ranged Melees (Hat of Discipline, Fish, Freezing Point etc)
DPS Ranged (Asteroid, Chicago, Dinner Blaster, Etymology, Hyperlaser)
Upgradable Ranged is very good if obtained (Pixel Gun, Suppresed Pistol etc)
Speed is a requirement; Jump, Healing (sometimes), Parry, I-frames and 2nd lives help
Wega Challenge
Practice Runner Glove; the lunge, sprint and wall climb techniques.
Any other additions/suggestions you want, you can comment
Timestamps:
00:03 Intro
00:57 10HBM
02:11 10HBM - Phase 2
04:23 Beta
06:01 Jean Down
06:37 Port Down
07:20 Xerroz Down
07:28 Clayman
10:12 Clayman - Phase 2
13:24 Contamination
15:47 Vent 1
17:21 Screen Cutscene
18:22 Elevator
22:09 Brute
22:58 Brute Phase 2
24:14 Klevprime
24:37 Slungus Prism - Klevprime
25:10 Klevinroto - Klevprime
25:55 Klevinroto - Phase 2
27:18 Man of Nature
28:24 Takeo - Man of Nature
29:55 Miracle Matter
31:24 Miracle Matter - Phase 2
33:05 Sage
35:26 Skeleton
36:53 Skeleton - Phase 2
38:45 Trash Gang
41:22 Port Down
42:28 Jean Down
42:56 Xerroz Down
43:05 Uncertified
43:15 Wave 1 - Uncertified
44:25 Wave 2 - Uncertified
46:01 Wave 3 - Uncertiifed
47:18 Wave 4 - Uncertified
49:05 Wave 5 Roulette
49:23 Count Dracombat (Wave 5)
51:33 Minos Dummy - (Wave 5)
54:06 Normal Wave (Wave 5)
54:41 Sir Combat - (Wave 5)
55:54 Sir Combat Phase 2
56:09 Wave 6 (Combat King)
59:10 Combat King - Phase 2
1:00:15 Weegee
1:02:51 Weegee - Phase 2
1:04:50 Wega Challenge
1:04:57 Wega - Maze 1
1:06:49 Rorys - Maze 1
1:08:09 Maltigi - Maze 1
1:10:27 Urio - Maze 1
1:11:27 Maze 2
1:12:20 Rorys - Maze 2
1:12:58 Maltigi - Maze 2
1:14:21 Urio - Maze 2
1:15:29 Maze U
1:16:17 Outtro