Trisomy 13, 18, 21 — Never Confuse Them Again | USMLE & COMLEX
Trisomy 13 (Patau), Trisomy 18 (Edwards), and Trisomy 21 (Down syndrome) — how to tell them apart on USMLE Step 1, COMLEX Level 1, and Pediatric Board Exams.
Board questions love testing whether you can distinguish the three major trisomies. This video breaks down the key distinguishing features so you never mix them up again — even under exam pressure.
We'll cover:
The defining clinical features that separate 13, 18, and 21
The survival pattern and why it matters for exam questions
How boards typically frame trisomy questions (and what they're really testing)
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