Why Hyaluronic Acid Fillers can Remain Longer than Expected, and How to Treat it

Опубликовано: 23 Июнь 2026
на канале: Amiya Prasad, M.D.
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New York facial cosmetic surgeon Amiya Prasad, M.D. reviews what can be done about hyaluronic acid fillers that haven’t metabolized, including: how these fillers can reach a deeper level than originally placed, or migrate past its original location; the possible causes of rare reactions to hyaluronic acid fillers; and how hyaluronidase treatments may not dissolve all the filler material, due to the practitioner’s inexperience:

0:22 - Introduction to hyaluronic acid fillers

1:11 - Dr. Prasad details his background training in cosmetic oculofacial plastic and reconstructive surgery, as well as his experience as an eyelid rejuvenation specialist

2:11 - Variables that can impact the longevity of hyaluronic acid fillers

2:20 - Why thicker fillers are placed in facial areas with little to no muscle movement, and how long they can last

2:38 - Why softer fillers are better for facial areas with more muscle movement

2:55 - How hyaluronic acid exists naturally in the body, and gradually metabolizes hyaluronic acid fillers

3:04 - The possible causes of rare reactions to hyaluronic acid fillers

3:30 - Why the rare incidence of filler encapsulation can prevent metabolization

4:00 - How encapsulated hyaluronic acid fillers can be dissolved with hyaluronidase without the need for surgery

4:22 - What hyaluronidase is

4:40 - Why the precise injection placement of hyaluronidase can be challenging

5:07 - How hyaluronic acid fillers can reach a deeper level than originally placed, which may require additional treatment

5:35 - How hyaluronic acid fillers can migrate past its original location

6:21 - How filler can still be encapsulated after it migrates

6:30 - What biofilm infection is and its effects

7:07 - Why the immune system cannot respond to biofilm infections, and how to treat it

7:30 - How hyaluronidase can dissolve the hyaluronic acid where the biofilm occurs

7:45 - Why biofilm is often misdiagnosed, and can be mistakenly treated

8:09 - Why hyaluronidase treatments may not dissolve all the filler material due to the practitioner’s lack of experience with tissue anatomy

8:56 - How hyaluronidase was previously used as part of the anesthetic procedure for cataract surgery

10:00 - The common fear of hyaluronidase affecting native hyaluronic acid, and why it’s not a significant issue

10:39 - How choosing a doctor with knowledge and experience of the anatomy of the treatment area, and how hyaluronidase can help achieve the best outcome

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