NEET PG-Causes of Isolated spontaneous abortion-OBS & Gynae
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The causes for isolated spontaneous abortion in 1st & 2nd trimester include:
Chromosomal abnormalities:
1.Aneuploidy M/C
2.Trisomy – 2nd best answer
3.Monosomy X (20%)- 3rd
4.Trisomy 16 (16%)
Germ plasm defects
Fetal causes
• Weather it is first or second trimester the m/c cause is chromosomal abnormality.
The frequency of abortion during 1st trimester is 50% and during 2nd is 35%