How Venlafaxine used for Social Anxiety?
How Venlafaxine used for Social Anxiety? #venlafaxine #socialanxiety #anxiety #socialanxietydisorder
In this video it is described that
Mode of action of Venlafaxine: Venlafaxine increases serotonin and norepinephrine levels in the central nervous system by blocking transport proteins and inhibiting their reuptake at the presynaptic terminal, ultimately enhancing the activation of postsynaptic receptors.
That help maintain mental balance.
Venlafaxine ER (Effexor XR) for Social anxiety.
Sertraline (Zoloft), Paroxetine (Paxil), and Venlafaxine ER (Effexor XR) are FDA-approved medications for social anxiety disorder.
Non-medication treatments, such as cognitive behavioral therapy (CBT) and support groups, may be helpful in relieving anxiety symptom.
People with social anxiety disorder also have difficulty performing daily activities, which can have negative consequences.
Extended-release (ER) venlafaxine (an SNRI) works by boosting brain levels of serotonin and norepinephrine, a chemical signal important for regulating stress.
After starting medications, it may take at least 4 to 6 weeks before experiencing any improvement in symptoms.
For some people, it may take even up to 12 weeks before the condition improves.
Usual Adult Dose for Social Anxiety Disorder:
Extended release: 75 mg orally once a day
Venlafaxine is an SNRI approved for first-line treatment of SAD(social anxiety disorder).
SNRIs work similarly to SSRIs; however, with SNRIs, concentrations of both serotonin and norepinephrine are increased.
In studies, venlafaxine was superior to placebo in reducing total social anxiety disorder symptom severity.
Head-to-head trials have not found one agent to be more effective than another.
One trial investigating the efficacy of venlafaxine and paroxetine concluded that these agents had similar response rates and were significantly superior to placebo.
Venlafaxine also has a latency period for its anxiolytic effect.
Warnings
You should not take venlafaxine if you have uncontrolled narrow-angle glaucoma.
Do not use venlafaxine within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.
Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor, such as: mood or behavioral changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Do not stop using venlafaxine without first talking to your doctor.
Do not give this medicine to anyone younger than 18 years old without the advice of a doctor. Venlafaxine is not FDA approved for use in children.
Venlafaxine side effects
Get emergency medical help if you have signs of an allergic reaction to venlafaxine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself.
Venlafaxine may cause serious side effects. Call your doctor at once if you have:
• blurred vision, eye pain or redness, seeing halos around lights;
• cough, chest tightness, trouble breathing;
• a seizure (convulsions);
• unusual bleeding - nosebleeds, bleeding gums, abnormal vaginal bleeding, any bleeding that will not stop;
• low blood sodium - headache, confusion, problems with thinking or memory, weakness, feeling unsteady; or
• severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.