Step 1: Go to the Action List (Actions menu - "show actions list" or just type ? (question mark))
Step 2: Type "screenset" in the Filter search box
Step 3: Add your own custom shortcuts for as many "Load Window Screenset (1, 2, 3)" actions as you like.
Optionally: add shortcuts to the "Save Window Screenset" actions as well. This way you can also save and re-save any of your screensets without having to open the Actions list each time.
Step 4: Rearrange your screen to your liking, and then run one of the "Save Window Screenset" actions. Name your screenset at the popup window and hit "save".
Step 5: Test your screenset by pressing the appropriate Load Screenset action.
Enjoy!
Leave any questions down below...
-CM