Overall 5-year survival of hepatocellular carcinoma (HCC) in the U.S. is ~20%. Survival depends on the state of HCC at the time of diagnosis. Dr. Nina Kim provides an overview of HCC in the context of chronic hepatitis B infection and discusses the indications and methods for HCC screening.
This December 2025 update incorporates new epidemiology information and updated screening recommendations included in the AASLD/IDSA 2025 Hepatitis B Guidance.