Meta-Analysis with CMA - Case Study: St. John's Wort
Tutorial on how to work with odds ratio or risk ratio in #metaanalysis. How to enter data, run analysis, estimate mean effect size, understand heterogeneity in effects, report the results, create plots. Also: perform subgroups analysis, meta-regression, and assess potential impact of publication bias.
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Chapters
0:00 Start
0:22 Basic Topics
2:42 Enter the data
11:16 Run Analysis
11:49 Random Effects
13:15 Mean Effect Size
15:50 Heterogeneity
29:10 How to explain the results
34:28 High-Resolution Plot
38:10 Sensitivity Analysis
43:39 Publication Bias / Small Study Effect
53:14 Explaining variation in effect size
55:45 Procedures to assess potential moderators
57:55 Subgroup Analysis
1:02:04 Issues in subgroup analysis - Random-effects within subgroups
1:05:29 Issues in subgroup analysis - Pool estimates of Tau-squared
1:11:15 Issues in subgroup analysis - Mixed model
1:13:48 Issues in subgroup analysis - Differences are observational, not causal
1:20:04 Issues in subgroup analysis - Hide overall summary
1:21:46 Meta-Regression