Vaccines are key to defeating infectious diseases, but their early trials are never easy. Professor McShane discusses setbacks in testing the first of a new generation of vaccines against tuberculosis, a disease that kills more than a million people a year, and discusses what the next ten years might bring.
The Lancet article on the study can be found here:
http://www.thelancet.com/journals/lan...
Early paper on safety and immune response:
http://www.ncbi.nlm.nih.gov/pmc/artic...
WHO factsheet on the current state of vaccine development:
http://www.who.int/vaccine_research/Q...