Wnt/ß-catenin Signaling Pathway
Hey Friends,
Wnt signaling is one of the most studied cellular pathways. Active Wnt/ß-catenin Signaling activates transcription of target genes that regulate cell fate decisions and cellular proliferation. Key players of the Wnt Pathway are often mutated in cancer.
More references for a detailed view on Wnt/ß-catenin:
https://www.ncbi.nlm.nih.gov/pmc/arti...
https://www.nature.com/articles/onc20...
Alberts, B. Molecular Biology of the Cell
Cheers
Henrik