Beat Brain of Cthulhu using the Ranger (Archer + Gunner) class in Master Mode on the Zenith (Get Fixxed Boi) seed, also known as, Legendary Mode (version 1.4.4.6). You can pick either Brain of Cthulhu (Crimson) or Eater of Worlds (Corruption), but one of them must be beaten first to upgrade your Pickaxe, so you can venture further into the Underworld to mine its stone and create Molten armor and weapons to advance. I find the Brain a little easier than the Eater, so I tackled it first.
To compare this fight with the same boss using the Calamity Mod and the True Melee class, see:
• Brain of Cthulhu [Terraria][Calamity][Reve...
Armor & Accessories:
Platinum Helmet
Platinum Chainmail
Platinum Greaves
Warding Shield of Cthulhu
Warding Magma Stone
Warding Magiluminescense
Warding Band of Regeneration
Warding Shark Tooth Necklace
Warding Spectre Boots
Weapons & Potions:
Unreal Tendon Bow with Jester Arrows for Phase 1
Demonic Mini-Shark with Musket Balls for Phase 2
Mythical Flinx Staff (to identify real Brain in Phase 2)
Slice of Cake
Rage Potion
Regeneration Potion
Swiftness Potion
Ironskin Potion
Shine Potion
Night Owl Potion
Endurance Potion
Archery Potion
Heartreach Potion