In this video, I have demonstrated how you can use python to perform Middle Mouse Button Click in case you don't have any hardware to do so.
Sorry for my bad English, I have said about clicking Up+down keys, but I actually meant to press them.
Link to the python script is given as follows:
https://drive.google.com/open?id=15xi...
If you have any queries then let me know in the comments below. I will be glad to reply to it.