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Hypo-Osmotic Swelling (HOS) Test

This fairly simple and relatively inexpensive test is based on the semipermeability (ability to allow fluid or elements to pass through it's membrane) of the intact sperm cell. A live sperm cell will "swell" when placed in a solution that is "hypo-osmotic", expanding the cell's volume. This test is easy to score and provides valuable information on the integrity and behavior of the cell membrane of the sperm tail.

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