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Maria Salvacion Gonzales
Yasmin Hashmi
Artem Shestakov
And Babar Hayatrana
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Systemic Lupus Erythematosus (SLE) also referred to Lupus is a chronic
multisystem autoimmune disorder of the connective tissues; sometimes referred to as a group
of syndromes due to the difference in how it can manifests in patients.
Autoimmune disorders occur when the body’s natural defenses against disease start attacking itself.
This disorder is difficult to diagnose. The patient can have periods of remission and flare-ups.
Inflammation can be seen in almost any area and every body system as the body’s immune response is lowered.
Lupus is known for a butterfly rash on the face, they were first seen in the early 1800’s.
The discovery of the systemic involvement was first
in the late 1800’’s with the joints lymphatic system, central nervous, neuromuscular and circulatory system/involvement.
In early 1900’s the butterfly rash was again seen on 20 pts, who also has systemic symptoms involving the lungs, heart, kidney and brain, which are now, known as advanced Lupus. 18 of those patients died in 2 years, which lead to start of research into disorder.