Complement System | Part 1 | Pathways, Activation, and MAC
This version may not be easier, but it is more colorful. Learn about the alternative, classical, and lectin pathways in general, why there are three pathways, and what their functions are.
I sincerely apologize for the spelling mistakes in Molecular Patterns Associated with Pathogens.
#PAMP #antibodies #innateimmunity
Kahoot! with video:
https://tinyurl.com/267v63du
Kahoot! without video:
https://tinyurl.com/6jj7d63t
Memes and infographics on Instagram and Facebook
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Some articles consulted for this broadcast:
Nonaka, M., Yoshizaki, F. (2004) Evolution of the complement system. Molecular Immunology, 40, 897-902. doi:10.1016/j.molimm.2003.10.009
Lambris, J. D., Ricklin, D., Geisbrech, B. V. (2008). Complement evasion by human pathogens. Nature Reviews Microbiology, 6, 132-142. doi:10.1038/nrmicro1824
Zipfel, P.F. (2009). Complement and immune defense: from innate immunity to human diseases. Immunology Letters, 126, 1-7. doi:10.1016/j.imlet.2009.07.005
Ricklin, D., Hajishengallis, G., Lambris, J. D. (2010). Complement: a key system for immune surveillance and homeostasis. Nature Immunology, 11, 785-797. doi:10.1038/ni.1923
Bohlson, S. S., Garred, P., Kemper, C., Tenner, A. J. (2019). Complement Nomenclature - Deconvoluted. Frontiers in Immunology, 10, 1308. doi: 10.3389/fimmu.2019.01308
International Complement Society Newsletter, December 2020:
https://www.complement.org/
https://36de0f2b-fe99-4e13-aacb-8da2b...
Recommended Reading:
Male, D, Stokes Peebles, R, Male, V. (2021). Immunology. Elsevier.
Thao, D, Richard A. Harvey, RA. (2021). LIR Immunology. LWW Wolters Kluwer.
Abbas, AK, Lichtman, AH, Pillai, S. (2020). Basic Immunology. Elsevier.
Punt, J., Strandford, S.A., Jones, P.P., Owen, J.A. (2020). Kuby. Immunology. McGrawHill.
Sompayrac, L.M. (2019). How the Immune System Works. Wiley-Blackwell
Tizard, I. (2019). Veterinary Immunology. Elsevier.
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Image by Paul Ehrlich:
Eduard Blum - https://wellcomeimages.org/indexplus/...
Modified with zoom and frame