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With the release of the Trials of the Ancestors league, we received a bunch of new unique items, many of them tied to the new league mechanic. Defiance of Destiny is seemingly the rarest new unique of them all, and it has a very special modifier which, to my knowledge, is the first of its kind. But how useful is it?

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#pathofexile #poe #pathofexile2 #poe2 #build #guide #tutorial #mechanics

0:00 Introduction
0:22 Defiance of Destiny
1:16 Mechanics Explained
2:04 Use Case
2:31 Example
4:55 Petrified Blood
5:40 Example with PB
7:23 Maximum Life Scaling
7:44 Closing

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