Cross-linking is common problem with capsule shells. In this video we will discuss mechanism and causes of cross-linking in gelatin capsules.
Many factors such as metal ions, carbonyl groups in API or excipients, exposure to temperature, etc are responsible factors. We willbdiscuss them in details in this video.
#gelatin #capsules
#dissolution
#usp #cross-linking
#formulation
#formulation development #condensation reaction