Thyroid hormones (synthesis) explained simply
In this video, you'll learn the synthesis of the thyroid hormones T3 (triiodothyronine) and T4 (thyroxine) step by step. Perfect for medical students, physiology exams, and endocrinology.
This video explains the synthesis of the thyroid hormones T3 (triiodothyronine) and T4 (thyroxine) step by step. You will learn:
• How iodide is taken up into thyrocytes via NIS
• The role of pendrin in transport into the colloid
• How TPO oxidizes iodide and forms MIT and DIT in the coupling reactions
• How thyroglobulin serves as a scaffold for hormone production
• How MIT + DIT → T3 and DIT + DIT → T4 are produced
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Medical knowledge explained simply and concisely for German students.
Feel free to leave topic suggestions for future videos in the comments.
ATTENTION:
The content is presented in a very simplified way to facilitate viewer understanding.
Timecodes:
0:00 Intro
0:05 Anatomy of the Thyroid Gland
0:25 Differences between T3 and T4
1:49 Hormone Synthesis
2:32 Sodium Idodides Symporter
2:50 Pendrin
3:10 Thyroid Peroxidase
3:35 Thyroglobulin
4:05 MIT and DIT
4:25 Conjugation
5:25 Reverse T3
5:49 Endocytosis and Cleavage
6:08 Summary
Search Keywords: T3, T4, thyroxine, triiodothyronine, thyroid gland, synthesis, endocrinology, thyroglobulin, iodine, pendrin, TPO, NIS, colloid, MIT, DIT, medical students, physiology, hormones.