Make sure to be on at least bios agesa 1.2.06b or higher.
Only touched bios settings is
RAM Setup, choose whatever fits your ram and motherboard.
And settings shown in this video, I would suggest starting with negative curves on 25 and work you way with CoreCycler to see if you can get stability.
https://github.com/sp00n/corecycler
Motherboard: Asus x570 ROG Crosshair VIII Hero
CPU: 5950X
All main component's watercooled.