Rheumatoid arthritis cured case |Permanent cure of Rheumatoid arthritis||
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Introduction
Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology marked by a symmetric, peripheral polyarthritis. It is the most common form of chronic inflammatory arthritis and often results in joint damage and physical disability. Because it is a systemic disease, RA may result in a variety of extraarticular manifestations, including fatigue, subcutaneous nodules, lung involvement, pericarditis, peripheral neuropathy, vasculitis, and hematologic abnormalities.
Clinical Features
The incidence of RA increases between 25 and 55 years of age, after which it plateaus until the age of 75 and then decreases. The presenting symptoms of RA typically result from inflammation of the joints, tendons, and bursae. Patients often complain of early morning joint stiffness lasting more than 1 hour and easing with physical activity. The earliest involved joints are typically the small joints of the hands and feet. The initial pattern of joint involvement may be monoarticular, oligoarticular (4 joints), or polyarticular (more than 5 joints), usually in a symmetric distribution. Some patients with an inflammatory arthritis will present with too few affected joints and other characteristic features to be classified as having RA—so-called undifferentiated inflammatory arthritis. Those with an undifferentiated arthritis, who are most likely to be diagnosed later with RA, have a higher number of tender and swollen joints, test positive for serum rheumatoid factor (RF) or anti-CCP antibodies, and have higher scores for physical disability.
Once the disease process of RA is established, the wrists, metacarpophalangeal (MCP), and proximal interphalangeal (PIP) joints stand out as the most frequently involved joints. Distal interphalangeal (DIP) joint involvement may occur in RA, but it usually is a manifestation of coexistent osteoarthritis. Flexor tendon tenosynovitis is a frequent hallmark of RA and leads to decreased range of motion, reduced grip strength, and "trigger" fingers. Progressive destruction of the joints and soft tissues may lead to chronic, irreversible deformities. Ulnar deviation results from subluxation of the MCP joints, with subluxation of the proximal phalanx to the volar side of the hand. Hyperextension of the PIP joint with flexion of the DIP joint ("swan-neck deformity"), flexion of the PIP joint with hyperextension of the DIP joint ("boutonnière deformity"), and subluxation of the first MCP joint with hyperextension of the first interphalangeal (IP) joint ("Z-line deformity") also may result from damage to the tendons, joint capsule, and other soft tissues in these small joints. Inflammation about the ulnar styloid and tenosynovitis of the extensor carpi ulnaris may cause subluxation of the distal ulna, resulting in a "piano-key movement" of the ulnar styloid. While metatarsophalangeal joint (MTP) involvement is a feature of early disease in the feet, the ankle and midtarsal regions are usually affected later in the course of disease and often predispose to pes planovalgus ("flat feet"). Large joints, including the knees and shoulders, are often affected in established disease, although these joints may remain asymptomatic for many years after onset.
People may experience:
Pain areas: in the joints, back, or muscles
Joints: stiffness, swelling, tenderness, or weakness
Whole body: fatigue, anaemia, or malaise
Skin: lumps or redness
Hand: bump on the finger or swelling
Also common: flare, dry mouth, physical deformity, or sensation of pins and needles
Incidence: More than 1 million cases per year (India)
FAQ:
Q. Is rheumatoid arthritis a serious condition?
A. RA is a very serious autoimmune disease, in which your immune system mistakenly attacks your own body's tissues and causes severe joint pain, stiffness, severe fatigue, and sometimes deformity, usually in the hands, shoulders, knees, and/or feet. It affects men, women, and children of all
Q. Does rheumatoid arthritis go away?
A. Doctor's Response: There is no cure for rheumatoid arthritis, but it can go into remission. Furthermore, treatments are getting better all the time, sometimes to the point a drug and lifestyle regimen can stop the symptoms in their tracks. As a rule, the severity of rheumatoid arthritis waxes and wanes
Some Autoimmune Diseases
Rheumatoid arthritis
psoriasis
alopecia areata
Vitiligo
Graves' disease
Hashimoto's thyroiditis
Hemolytic anemia
Thrombocytopenic purpura
Multiple sclerosis
Acute rheumatic fever
Systemic lupus erythematosus
Granulomatosis with polyangiitis (Wegener's)
Antiphospholipid syndrome
Sjögren's syndrome
Systemic necrotizing vasculitis
Reference:
Harrison's Principles of Internal Medicine
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