In this special episode of the Innovation Circle, held in collaboration with the Joint Research Centre (JRC) and the Directorate-General for Research and Innovation (DG RTD) of the European Commission, we recapped key insights from the 2024 ETIN Transformative Innovation Action Forum, which took place from 1st to 3rd October in Brussels. Experts addressed the barriers and opportunities for transformative innovation, explored the necessary actions and processes to drive meaningful change, and highlighted contributions at personal, organizational, and institutional levels. Real-life examples demonstrated the impact of systematic approaches and tools, while the discussion concluded by identifying key areas for future collaboration and cross-sectoral opportunities, opening new pathways for learning and collective action toward lasting transformative impact.