Anime Upscaling Test - 1080p to 4K using waifu2x
Anime - Castlevania S3 E1
Conclusion: I think the original source file I was working with was too compressed for waifu2x to be able to change much; it's pretty fuzzy for 1080p and waifu2x only works well when only thing it needs to change is the limitations of the native resolution, not bad picture quality.