Chronic pancreatitis - causes, symptoms and treatment
If you want to support the channel:
PayPal: [email protected]
Transfer: 12 1090 2750 0000 0001 3690 7883 Knowledge test (unfortunately, it doesn't work because the trial period has expired):
fyrebox.com/play/wdnmlkdxy6nz9dejdz/
Chronic Pancreatitis
Chronic pancreatitis is a long-term process involving the gradual replacement of pancreatic tissue
with fibrous connective tissue, which ultimately leads to pancreatic failure.
Chronic pancreatitis most often occurs
around the ages of 40 to 50. Men are affected about 1.5 times more often.
The most common cause is alcohol, accounting for about 70%
of all cases.
Other causes include genetic diseases, such as cystic fibrosis.
In 20% of cases, the cause cannot be determined. Causes
This is referred to as an idiopathic cause.
One cause is autoimmune pancreatitis, or AZT for short.
There are two types of AZT:
Type one, in which there is an increase in IgG4 immunoglobulin, occurs most often in people aged 60-70, and type two, in which there is no increase in IgG4 immunoglobulin, occurs most often in young people.
The most common symptoms are:
abdominal pain, usually after a meal,
exocrine insufficiency, which manifests itself as
chronic diarrhea and flatulence.
Endocrine insufficiency, which manifests as diabetes
and weight loss.
Diagnosis is based on complete blood counts.
Amylase and lipase may be elevated, but not necessarily.
A key element in diagnosis is a history, where
a history of alcohol abuse is noted.
An ultrasound examination is also performed, which can reveal
pancreatic enlargement and fibrosis.
If autoimmune pancreatitis is suspected, then Immunoglobulin IgG4 is administered.
Treatment primarily involves a healthy lifestyle,
which means avoiding alcohol and smoking. Pancreatic enzymes,
as well as fat-soluble vitamins such as A, D, E, and K, are used for digestive problems.
The most common complication is pseudocyst,
which occurs in approximately 30% of patients.
Small ones produce no symptoms.
Large ones cause discomfort.
Pseudocysts are most often treated endoscopically.
Another complication is bile duct stenosis.
About 4% of patients develop pancreatic cancer.
Effective treatment of alcoholism is crucial for prognosis,
because alcohol consumption significantly worsens the prognosis.
If treatment for alcoholism is ineffective, the mortality rate is
30% within 10 years, and 50% within 20 years.