Brain Boosting Methylene Blue || Benefits, Dosing, & Side Effects
🧠 “Brain Boosting Methylene Blue” — Benefits, Dosing, Side Effects
Ready to supercharge your brain and mitochondria? In this video, Dr. Michael Moeller, ND, breaks down everything you need to know about Methylene Blue — from how it works to how to use it safely for cognitive performance, mitochondrial function, and more.
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___________Timestamp/Topics of Interest___________
@0:00 – Intro
@1:05 – What is Methylene Blue?
@2:12 – Mechanisms of Action
Reduces methemoglobin back to functional hemoglobin
Antioxidant & antimicrobial (pre-penicillin antiseptic)
Vasoconstriction via nitric oxide inhibition
Reduces blood-brain barrier permeability & neuroinflammation
Powerful nootropic effects via mitochondrial support
@4:33 – Biohacking Benefits
Boosts mitochondrial Complex IV by 30%
Increases oxygen consumption by 37–70%
Improves glucose uptake & ATP production
Enhances memory, mood, and reaction time
May delay or reverse cellular aging
Antidepressant & anxiolytic effects (MAOi)
@8:30 – Clinical & Experimental Uses
Methemoglobinemia
Low blood pressure, shock
Surgical dye, fish tank treatments
Malaria, UTIs, Alzheimer’s, dementia, bipolar
COVID-19, cancer, priapism, heparin reversal
@11:58 – Contraindications / Drug Interactions
SSRIs, SNRIs, antidepressants → Serotonin Syndrome risk (fatal)
MAO inhibitors
G6PD deficiency
Liver/kidney disease, vital sign instability
@13:30 – Side Effects
Blue/green urine
Sweating, dizziness, hot/cold flashes
Hemolysis in G6PD deficiency
Possible allergic reaction or anaphylaxis
Unknown long-term effects
@15:25 – Dosing & Administration
Oral: 4–250 mg
IV: 1–2 mg/kg over 5–30 min
Half-life: ~5–7 hours
Safe: under 2 mg/kg | Risk of serotonin syndrome: over 5 mg/kg
Alzheimer’s/UTI prevention: 65 mg TID
Malaria: 36–72 mg/kg over 3 days
@17:11 – Hormetic Effect
More is not better
Low dose (0.05 mg/kg) = cognitive enhancement
High dose (50 mg/kg) = amnesia
@18:25 Sources
https://pubmed.ncbi.nlm.nih.gov/17928....
https://www.ncbi.nlm.nih.gov/pmc/arti...
https://www.ncbi.nlm.nih.gov/books/NB....
https://www.sciencedirect.com/topics/...
https://www.sciencedirect.com/science...
https://link.springer.com/article/10....
https://en.wikipedia.org/wiki/Methyle....
https://www.drugs.com/mtm/methylene-b...
https://my.clevelandclinic.org/health...
https://pubmed.ncbi.nlm.nih.gov/34019...
https://riviste.fupress.net/index.php...
https://www.frontiersin.org/articles/...
http://www.biomed.cas.cz/physiolres/p...
https://clinicaltrials.gov/ct2/show/N...
https://www.ncbi.nlm.nih.gov/labs/pmc...
https://www.ncbi.nlm.nih.gov/labs/pmc...
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🔴==========⚠️ Full Disclaimer⚠️==========🔴
The information provided in this video is for entertainment purposes only and IS NOT MEDICAL ADVICE. If you have questions about your health contact a medical professional.This content is strictly the opinion of Dr. Michael Moeller and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Michael Moeller nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program
#MethyleneBlue
#Nootropics
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