Stomach Cancer Pathology and Molecular Types
Gastric cancer encompasses diverse histologic and molecular subtypes that dictate treatment responses, from Lauren's intestinal vs. diffuse types to TCGA's CIN, GS, MSI, and EBV categories. Key biomarkers like HER2, PD-L1 CPS, and MSI status guide targeted therapies and immunotherapy. This video equips patients and clinicians with insights to interpret pathology reports and optimize care.
This content is entirely based on medical research and evidence. Content carefully curated by Mr Saboor Khan FRCS FACS, PhD, Consultant Surgeon.
00:00 Introduction
01:01 Number One: The Lauren Classification — Intestinal Versus Diffuse Histology
02:12 Signet Ring Cell Carcinoma and Prognosis
03:00 The WHO Classification
03:30 The Four Molecular Subtypes — This Is Where It Gets Truly Important
05:15 Biomarker Testing That Guides Therapy
06:57 The Correa Cascade
07:45 Action Section
08:12 Conclusion
Explore the full video series for a broader understanding of your condition with evidence-based content — check out the playlist.
This content is for educational purposes only. Personal medical decisions must be made with your treating team. Patients should not draw inferences about their own condition from this content. Every effort is made to ensure content is current at time of production; however, this cannot be guaranteed.