Yep.
Note: Like Tanjiro's True Zero to Death Combo, Dio's fourth ability "The World" hits/effects all players in any state, or pre-hits/effects someone recovering before an action can be made, making the move unavoidable. This is also what allows him to get a second wall-bounce in the same combo (Although the combo counter might reset, the combo is true and can't be avoided unless a separate player attacks you during your starting animation for "The World").