Mining the molecular noise: fluorescence fluctuation image analysis of microscopy and...
Presented By: Paul Wiseman, PhD
Speaker Biography: Paul Wiseman obtained his B.Sc. (Honours) from St. Francis Xavier University in 1989 and Ph.D. in Chemistry from the University of Western Ontario in 1995 where he held a NSERC postgraduate research fellowship. Afterwards he was awarded a Japan Society for the Promotion of Science postdoctoral fellowship at the University of Tokyo and Nagoya University (with Prof. Akihiro Kusumi), and later became a LJIS interdisciplinary postdoctoral research fellow at the University of California, San Diego (with Prof. Kent Wilson).
Webinar: Mining the molecular noise: fluorescence fluctuation image analysis of microscopy and super-resolution microscopy images reveals biomolecule interactions & transport maps in living cells
Webinar Abstract: The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been developed to measure these properties in cells, although most have relied on fluorescence microscopy imaging as the window for measurement of labeled macromolecules in living cells. Image correlation methods are an extension of fluorescence fluctuation spectroscopy that can measure protein-protein interactions and macromolecular transport properties from input fluorescence microscopy images of living cells.