A CRISPR Cas12a Assisted in Vitro Diagnostic Tool for Identification and Quantification of Single Cp
Presented By: Nienke van Dongen, MSc
Speaker Biography: Nienke van Dongen received her BSc and MSc in molecular life sciences from Wageningen University, The Netherlands. During her MSc, she specialized in physical chemistry and took part in the top sector chemistry program for talented students in analytical chemistry (TI-COAST)...
Webinar: A CRISPR Cas12a Assisted in Vitro Diagnostic Tool for Identification and Quantification of Single Cp
Webinar Abstract: Cancer, as a disease, starts with a change in the genome that results in the downregulation of genes involved in "normal" cell behavior. This genetic change can either be induced by a change in the DNA code (mutation) or a change that does not affect the genetic code but instead influences the way this code can be read. The latter is called an epigenetic alteration. While cytosine methylation is a healthy process, methylation of promoter CpG islands has also been shown to be a critical hallmark in many cancer cells. This is because specific genes on the DNA must always be expressed to prevent a "normal" cell from becoming a cancer cell...
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