Resident Evil 4 - Capacity Compliance (NG+ easy dumb strat, minimal aiming required)
this is not a practical strat, but it is easy and it does work. I found that in my NG+ Minimalist + Silent Stranger run (Pistol/Knife only + no merchant) I had an inventory full of random things. In this case, I had amassed 20 some flashbangs (I think I had like 15, and then I crafted 5 more because... well I didn't know what else to do with the Large Resources during my pistol/knife run)
This is NG+ strat because I doubt you'll have this many flashbangs by this point in a regular new file.
So why would you do it this way? If you're lazy and don't wanna aim to shoot. (The flashbang has a huge radius. Anyone who is close enough to matter will get stunned)
If you're aiming to platinum this game, you're already gonna do like a bunch of runs, so you may as well pick up this trophy during one of them.