A skilled martial artist trained in Karate and Kenjutsu, Etsuko was a member of Sonny Chiba's "Japan Action Club" (JAC) and appeared in several film and TV productions with Chiba, Hiroyuki Sanada, and other members of the JAC, including her big screen debut in Bodyguard Kiba 2 (1973), The Street Fighter (1974), Killing Machine (1975), The Gorilla Seven TV series (1975), The Defensive Power of Aikido (1975), Shogun's Samurai (aka The Yagyu Clan Conspiracy) (1978), The Yagyu Conspiracy TV series (1978), Message from Space (1978), Shadow Warriors I-V TV series (1980-1985), Shogun's Ninja (1980), Roaring Fire (1982), and Legend of the Eight Samurai (1983).
Etsuko was also the lead in a number of films and TV series, starring in the Sister Street Fighter trilogy (1974-1975), The 13 Steps of Maki (1975), The Magnificent Chase (1975), Dragon Princess (1976), Lethal Woman: Fifth Level Fist (1976), the Yagyu Jubei Abaretabi TV series (1982-1983) where she reprised her role as Akane Yagyū alongside Sonny Chiba as Jūbei Yagyū from Shogun's Samurai (1978) and The Yagyu Conspiracy (1978), and The Second is a Christian (1985) an action comedy about a nun who becomes the successor to the head of a Yakuza group.