Can't Open HandBrake on Windows? Try These Fixes
If you can't open HandBrake on Windows, try:
Update HandBrake.
Restart your computer.
Run HandBrake as an administrator.
Install Microsoft .NET Framework.
Uninstall and reinstall HandBrake.
Contact HandBrake support.
If you're still having trouble, try disabling your VPN, adding HandBrake to the antivirus exclusion list, and making sure your laptop is plugged in and charging.