Multiple Sclerosis is Becoming Milder [Data Presented by Neurologist]
On average, the rate of relapses, accumulation of disability, and even mortality is decreasing in people with multiple sclerosis. This video shows historical and modern studies, demonstrating the clear trend. But why is this happening? Is it better diagnosis, a change in diagnostic criteria, or disease modifying therapies?
Selected Sources:
Data-driven risk/benefit estimator for multiple sclerosis therapies: https://www.medrxiv.org/content/10.11...
Changes in the Risk of Reaching Multiple Sclerosis Disability Milestones In Recent DecadesA Nationwide Population-Based Cohort Study in Sweden: https://jamanetwork.com/journals/jama...
Natural history of multiple sclerosis (queen square data): https://jnnp.bmj.com/content/jnnp/55/...
Long-term evolution of multiple sclerosis disability in the treatment era: https://pubmed.ncbi.nlm.nih.gov/27464...
Trends in survival and cause of death in Danish patients with multiple sclerosis: https://academic.oup.com/brain/articl...
Mortality and cause of death in multiple sclerosis in western Norway 1950–2021: a registry-based linkage study: https://jnnp.bmj.com/content/93/11/11...
PROGNOSIS and treatment of disseminated sclerosis: https://pubmed.ncbi.nlm.nih.gov/13584...
THE COURSE OF MULTIPLE SCLEROSIS: https://onlinelibrary.wiley.com/doi/a...
Multiple sclerosis: a review: https://pmc.ncbi.nlm.nih.gov/articles...
Age and disability accumulation in multiple sclerosis: https://pmc.ncbi.nlm.nih.gov/articles... at disability milestones in multiple sclerosis : https://academic.oup.com/brain/articl...
Clinical course of multiple sclerosis: A nationwide cohort study: https://neuroreg.se/media/1vrf5n51/ma...
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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.
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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.