This video reviews phase III clinical trial results on tolebrutinib presented at ECTRIMS. The GEMINI trials studied tolebrutinib vs. aubagio in relapsing MS, and the HERCULES trial studied tolebrutinib vs. placebo in progressive MS.
Tolebrutinib Effective for Secondary Progressive Multiple Sclerosis (Sanofi Press Release): • Tolebrutinib Effective for Secondary Progr...
Bruton's Tyrosine Kinase Inhibitors for Multiple Sclerosis Explained by Neurologist: • Bruton's Tyrosine Kinase Inhibitors for Mu...
Selected Sources:
Sanofi lifts lid on MS data behind tolebrutinib’s mixed phase 3 scorecard, plans ‘24 approval filings: https://www.fiercebiotech.com/biotech...
Press Release: Tolebrutinib demonstrated a 31% delay in time to onset of confirmed disability progression in non-relapsing secondary progressive multiple sclerosis phase 3 study: https://www.globenewswire.com/news-re...
Twitter post by Professor Bart on Gemini Data: https://x.com/bart_professor/status/1...
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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.
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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.