Mixing and Matching Covid Vaccines
The C.D.C. said on Thursday that Americans could choose a booster dose of a vaccine different from the one they had initially received — the so-called mix-and-match strategy.
Preliminary evidence strongly suggests that mixing two Covid vaccine types produces a stronger immune response than matching the booster to the initial vaccine.
Booster doses of an mRNA vaccine (Pfizer-BioNTech or Moderna) seem to raise antibody levels higher than a booster dose of the Johnson & Johnson vaccine.