The Environment and Vasculitis: A Closer Look
0:00
0:46 Introduction of Dr. Guy Katz
4:40 What is autoimmunity?
7:38 Genetics.
9:02 What are environmental triggers?
11:36 How to prove something causes vasculitis.
13:16 Observational studies.
14:32 Challenge with observational studies.
17:08 Trigger of disease onset vs. flares.
19:14 Environmental triggers of vasculitis.
19:57 Infections.
22:46 COVID-19
23:20 Seasonality.
24:45 Airborne exposures.
25:51 Occupational exposures.
27:01 Cigarette smoke.
28:27 Medications and drugs.
30:09 On an individual level.
31:51 Final thoughts.
35:42 Q: Is there more research into COVID possibly triggering vasculitis?
36:42 Q: Can changes in barometric pressure trigger symptoms?
37:40 Q: Can a medication exposure that triggers vasculitis only start to show certain symptoms a month later?
40:55 Q: Can exercise be considered an environmental trigger?
42:02 Q: What about silica as a possible environmental trigger?
44:18 Q: The environmental triggers of vasculitis that you mentioned initially - was that at disease onset or flares?
45:47 Q: Is autoimmune disease inherited since there is a genetic component?
47:21 Q: What about exposure to mold and jet fuel?
49:21 Q: I am confused about when something could cause vasculitis and when something requires the immune system.
50:39 Q: Can you name the top three possible environmental factors associated with ANCA-vasculitis?
52:19 Q: How can you get involved in the studies cited in the presentation?
54:44 Q: What about the Shingrix vaccine?
57:46 Q: Do you expect more researchers to look at this area of potential environmental triggers with vasculitis?
58:35 Q: Has the doctor ever seen a case where family members were both exposed to the same element—diagnosed with vasculitis?
Vasculitis and the Environment: A Closer Look
August 2024
Download a PDF of Dr. Katz's slide presentation: https://www.vasculitisfoundation.org/...