Mexidol, omeprazole and prednisolone: effect on sperm. Should you postpone pregnancy planning?
Mexidol, omeprazole and prednisolone: effect on sperm. Should you postpone pregnancy planning? Sign up for an online consultation at the CIR by following the link https://vk.cc/ccpWoV
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In this video, urologist-andrologist of the CIR, PhD, Zhivulko Andrey Romanovich, https://vk.cc/9zlrrh, answers the question: "For the treatment of optic nerve neuritis, a neurologist prescribed prednisolone, omeprazole, mexidol to my husband. We are actively planning. Will taking these drugs affect the quality of sperm? Should I wait 3 months after a complete renewal of sperm? When it is important to consider that I am over 40, every cycle counts. Low anti-Müllerian hormone."
Ocular neuritis is a serious problem. We cannot cancel drugs prescribed for such indications. From what you named, in principle, there is nothing that would directly interfere. That is, in fact, in general, there are not so many such drugs, which are directly expressed, against the background of which, according to the male factor, it is not recommended to plan a pregnancy, because these drugs have a certain taratogenic effect and disrupt spermatogenesis very strongly and lead to an increase in the level of aneuploidy, primarily of spermatozoa. Therefore, here, I think that, in principle, it is possible to plan. It is clear that one cannot completely exclude the influence. Studies that will evaluate the effect of therapy, drugs on spermatogenesis are very complex studies. And there may not be a pronounced effect, but it is very difficult to completely exclude any influence at all, in principle. That is, it is impossible to say with absolute certainty. There may be an effect, but it is not necessarily such that it is immediately detected. Therefore, this is a very complex study and not all drugs have undergone these studies. Therefore, in such a situation, I think it is worth trying. Considering that the age is, indeed, 40 years, there may also be questions regarding the female factor.
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