Antiulcer Activity by Pylorus Ligation Method Explained in English | Ex-Pharm Software Demonstration
Antiulcer Activity by Pylorus Ligation Method explained in english | Ex-Pharm Software Demonstration
Above video in Hindi Link: • Antiulcer Activity by Pylorus Ligation Met...
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In this video, we demonstrate the Antiulcer Activity by Pylorus Ligation Method in Rats using Ex-Pharm Software. The step-by-step procedure includes:
• How to ligate the pylorus in experimental rats/mice.
• Suturing of the abdominal wound after pylorus ligation.
• Removal of the stomach and cutting along the greater curvature.
• Observation of gastric mucosa to identify ulcer formation.
• Demonstration of parameters such as gastric volume, pH, total acidity, and ulcer index.
• Effect of Omeprazole treatment, showing reduced gastric secretion and protective antiulcer activity.
This video is designed for B.Pharm and M.Pharm students to understand the experimental pharmacology of antiulcer drugs. After 19 hours of pylorus ligation, accumulation of gastric content and ulcer formation is clearly demonstrated, providing insight into the role of antisecretory drugs like omeprazole in reducing gastric damage. The aim of the present study is to demonstrate the antiulcer activity of drugs using pylorus ligand (SHAY) rat model. This was first demonstrated by Shay in 1945. Ligation of rat pylorus results gastric acid accumulation in the fore-stomach leads to acute gastric ulcers. This procedure is used to screen the drugs for their anti-secretary and antiulcer activity.
Pylorus ligation demonstration using expharm Software
Antiulcer Activity By Pylorus Ligation Method in Rat | Ex-Pharm Software
Keywords
Antiulcer activity, pylorus ligation method, rat experiment, Ex-Pharm software, antiulcer drugs, gastric ulcer, peptic ulcer, omeprazole, stomach secretion, pyloric ligation procedure, stomach removal, ulcer observation, stomach tissue preparation, gastric acidity, pharmacology practical, B.Pharm experiment, M.Pharm practical, ulcer index, gastric volume, acidity measurement, experimental pharmacology
Best Titles
1. Antiulcer Activity by Pylorus Ligation Method in Rats | Ex-Pharm Software Demonstration
2. Pylorus Ligation Method for Antiulcer Activity | Pharmacology Practical for B.Pharm & M.Pharm
3. Experimental Demonstration of Antiulcer Effect of Omeprazole Using Pylorus Ligation in Rats
4. Step-by-Step Pylorus Ligation Method | Antiulcer Activity Study with Ex-Pharm Software
5. Pharmacology Experiment: Antiulcer Activity by Pylorus Ligation Method (Rat Model)
Please click the links for the In-vivo study protocols: https://www.researchsop.com/2022/04/L...