One strand is the codon and one is the anti-codon. The strands are the same until the promoter finds its recognition site. The orientation of the promoter determines which strand is the codon.
supporting documentation:
https://app.box.com/s/vkqsotttbkqavj5...
If the promoter specifies the codon, then the promoter has two possible orientations. each specifying one of the two possibilities. This video is a little weird, but presents an original idea.
• Transcription factors and the one arm...