Alzheimer’s Breakthrough? Methylene Blue, Ketones & Light Therapy Explained I Beyond Healthspan
In this episode of Beyond Healthspan, Brandon and Dr. Richard LaFountain explore Dr. Francisco Gonzalez-Lima’s groundbreaking work on Alzheimer’s disease. Learn why the traditional amyloid plaque theory may be incomplete, and how the “vascular hypometabolism” model reframes Alzheimer’s as a metabolic and mitochondrial disorder.
We discuss:
Why amyloid plaques may be a symptom—not the cause—of Alzheimer’s
The role of cytochrome c oxidase in brain energy metabolism
How methylene blue, ketones, and light therapy may support brain health
Practical prevention and intervention strategies
Timestamps:
00:00 – Introduction & Podcast Overview
01:37 – Why Alzheimer’s Research Has Been Slow to Progress
04:53 – The Amyloid Plaque Hypothesis Explained
12:51 – Why Plaques & Tangles Aren’t the Whole Story
16:25 – The Vascular Hypometabolism Hypothesis
22:05 – FDG-PET Imaging & Brain Energy Deficits
27:08 – The Nun Study & Rethinking Alzheimer’s Cause
34:07 – Cytochrome c Oxidase and Mitochondrial Function
44:31 – Methylene Blue as a Mitochondrial Enhancer
52:04 – Ketones and the Brain Energy Gap
1:02:47 – Near-Infrared Light Therapy for Brain Health
To Learn More visit gethealthspan.com