Hybrid molecules are chemical entities that are formed by the combination of structural features of two differently active fragments for the creation of a modified scaffold with improved and enhanced activities.
1 The synthesis of hybrid molecules and exploring their pharmacological potential has fascinated a great deal of interest from the last two decades.
2 It has emerged as a powerful tool in drug discovery programs.
3 In this presentation, the designing, synthesis, and biological evaluation of novel hybrid molecules will be discussed.