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Lung biopsy is an essential tool for the characterization of pulmonary lesion of undetermined origin. Bronchoscopy is the preferred modality for central lesions whereas interventional radiology is usually reserved for peripheral ones. CT-guided biopsy ( • CT-guided Lung Biopsy procedure and technique ) is the most common modality, probably followed by cone-beam CT but, when the lesions are subpleural, ultrasound can be an extremely advantageous tool as it allows a real-time view of the nodule and needle
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